Neuropharmacological research is strongly dependent on the availability of sensitive analysis methods for neurotransmitters, neuromodulators and biomarkers in the brain and plasma samples of rodents. The team of Ann Van Eeckhaut focuses on the development of newer, faster, better, and more sensitive liquid chromatography tandem mass spectrometry methods for analysis of volume-limited samples. They apply targeted and untargeted approaches in their research to study small molecule brain mediators and neuropeptides.