KEY PUBLICATIONS
2026
Chemogenetic astrocyte modulation reduces spontaneous hippocampal discharges and metabolite changes in an epilepsy mouse model
Nestor L, Van Den Herrewegen Y, Dyer M, Bossuyt J, Hendrix E, Buckinx A, Bournons S, Viaene J, Heyden YV, Van de Casteele M, Van Eeckhaut A, Smolders I, De Bundel D.
Transcranial alternating current stimulation at 10 Hz promotes oligodendrogenesis and reduces g-ratio after cuprizone-induced demyelination
Thomas Jonathan Scheinok, Mathieu Grognard, Miguel D'Haeseleer, Guy Nagels, Dimitri De Bundel, Jeroen Van Schependom
GPR35 modulates Nav1.9 gating and sensory neuron excitability
Margaux Theys, Jolien Vander Cruyssen, Juan Salvatierra, Frank Bosmans
Differential Regulation of β1-Dependent Voltage Shifts and Kinetic Modulation by an Extracellular Glutamate in Nav1.6 VSDIV
Maxime Lammens, Jolien De Waele, Alain J Labro, Filip Van Petegem, Frank Bosmans
Channeling teamwork: ATP and lipids cooperate to gate P2X receptors
Frank Bosmans, Toshimitsu Kawate
A Neurocutaneous Nav1.8 Channelopathy Underlies a Genetic Subtype of Primary Idiopathic Hyperhidrosis
Frank Bosmans
Recent developments in plasma sample preparation methods for targeted metabolomics studies with liquid chromatography mass spectrometry
Phaedra Verding, Yvan Vander Heyden, Ann Van Eeckhaut, Debby Mangelings
Effects of different Extraction Methods and Arginine Modification on the Physicochemical Properties and Biological Activities of Fungal and Slime Mold Melanins
Tran N.B. Lai, Anh Thy Nguyen Ngoc, Anh Vy Dang Nguyen, Yen T.H. Tran, Linh H. Doan, Debby Mangelings, Yvan Vander Heyden, Ann Van Eeckhaut, Hanh T.M. Tran
Treat: A Multicentre Cross-sectional TReatment Evaluation of Apparent Resistant hyperTension in Belgium
Sofie Brouwers, Huart Justine, Chabot Mathilde, Van Nieuwenhuyse Bregt, De Bacquer Dirk, Munhoz Daniel
Use of proton pump inhibitors in children in a tertiary hospital in Belgium
Eline Tommelein, Stephanie Wuyts, Fien Bockstal, Michelle Viljoen, Nicole Keuler, Melina Simon, Pieter Cornu, Gerlant van Berlaer
Peri-Surgical Support: Experiences of Breastfeeding Women
Lena De Hondt, Santina L Gorsen, Joke Muyldermans, Eline Tommelein
2025
A Bright Future for Photopharmaceuticals Addressing Central Nervous System Disorders: State of the Art and Challenges Toward Clinical Translation
Rudolf L Z Ganzoni, Sofie S Bournons, Erick M Carreira, Dimitri De Bundel, Ilse Smolders
Association of dysautonomia with refractory ventricular tachyarrhythmia in patients requiring thoracoscopic surgical cardiac sympathetic denervation
Andrei Gurau, Dianela Perdomo, Hamza Khan, Kelsey Melinosky, Anna Chudnovets, Jacob Blum, Mahmoud Kutmah, Victor Yang, Albert Leng, Arjun Menta, Xiyu Zhao, Suguru Yamauchi, Kristen Rodgers, Kathryn Ecoff, Errol Bush, Andreas S Barth, Malcolm Brock, Frank Bosmans, Jinny S Ha
A robust expression system reveals distinct gating mechanisms and calmodulin regulation of NaV1.9 channels
Margaux Theys, Jolien De Waele, Sharang Garud, Katrien Willegems, Filip Van Petegem, Frank Bosmans
2024
Chemogenetic Approaches to Study Astrocytes at Glutamatergic Synapses
Liam Nestor, Yana Van Den Herrewegen, Zuner A. Bortolotto, Dimitri De Bundel, Ilse Smolders
Neuromedin U Neurons in the Edinger-Westphal Nucleus Respond to Alcohol Without Interfering with the Urocortin 1 Response
Mireia Medrano, Wissal Allaoui, Ra'fat Ehab Salim Haddad, Leila Makrini-Maleville, Emmanuel Valjent, Ilse Smolders, Viktória Kormos, Balázs Gaszner, Dimitri De Bundel
Regulatory T cells as a possible new target in epilepsy?
Evelien Hendrix, Maxime Vande Vyver, Matthew Holt, Ilse Smolders
Subclinical epileptiform activity in the Alzheimer continuum: association with disease, cognition and detection method
Amber Nous, Laura Seynaeve, Odile Feys, Vincent Wens, Xavier De Tiège, Pieter Van Mierlo, Amir G Baroumand, Koenraad Nieboer, Gert-Jan Allemeersch, Shana Mangelschots, Veronique Michiels, Julie van der Zee, Christine Van Broeckhoven, Annemie Ribbens, Ruben Houbrechts, Sara De Witte, Mandy Melissa Jane Wittens, Maria Bjerke, Caroline Vanlersberghe, Sarah Ceyssens, Guy Nagels, Ilse Smolders, Sebastiaan Engelborghs
Targeted Chiral Metabolomics of D-Amino Acids: Their Emerging Role as Potential Biomarkers in Neurological Diseases with a Focus on Their Liquid Chromatography–Mass Spectrometry Analysis upon Chiral Derivatization
Cinzia Lella, Liam Nestor, Dimitri De Bundel, Yvan Vander Heyden, Ann Van Eeckhaut
Quantification of ADHD medication in biological fluids of pregnant and breastfeeding women with liquid chromatography: a comprehensive review
Lena De Hondt, Charlotte Cosemans, Michelle Plusquin, Debby Mangelings, Ann Van Eeckhaut, Eline Tommelein
ω-Grammotoxin-SIA inhibits voltage-gated Na+ channel currents
Rita de Cássia Collaço, Filip Van Petegem, Frank Bosmans
A MULTI-HIT MODEL OF LONG COVID PATHOPHYSIOLOGY: THE INTERACTION BETWEEN IMMUNE TRIGGERS AND NERVOUS SYSTEM SIGNALING
Malcolm V Brock, Frank Bosmans
2023
Neurofilament light chain: A possible fluid biomarker in the intrahippocampal kainic acid mouse model for chronic epilepsy?
Marie-Laure Custers, Maxime Vande Vyver, Lea Kaltenböck, Kurt Barbé, Maria Bjerke, Ann Van Eeckhaut, Ilse Smolders
Improving the LC-MS/MS analysis of neuromedin U-8 and neuromedin S by minimizing their adsorption behavior and optimizing UHPLC and MS parameters
Jana Bongaerts, Dimitri De Bundel, Ilse Smolders, Debby Mangelings, Yvan Vander Heyden, Ann Van Eeckhaut
Unravelling the brain metabolome: A review of liquid chromatography - mass spectrometry strategies for extracellular brain metabolomics
Liam Nestor, Dimitri De Bundel, Yvan Vander Heyden, Ilse Smolders, Ann Van Eeckhaut
2022
Unraveling the Effects of GSK-3β Isoform Modulation against Limbic Seizures and in the 6 Hz Electrical Kindling Model for Epileptogenesis
Najat Aourz, Fred Van Leuven, Wissal Allaoui, Ann Van Eeckhaut, Dimitri De Bundel, Ilse Smolders
2021
Applicability of cerebral open flow microperfusion and microdialysis to quantify a brain-penetrating nanobody in mice
Marie-Laure Custers, Yessica Wouters, Tom Jaspers, Dimitri De Bundel, Maarten Dewilde, Ann Van Eeckhaut, Ilse Smolders
2020
CE-MS metabolic profiling of volume-restricted plasma samples from an acute mouse model for epileptic seizures to discover potentially involved metabolomic features.
Karen Segers, Wei Zhang, Najat Aourz, Jana Bongaerts, Sven Declerck, Debby Mangelings, Thomas Hankemeier, Dimitri De Bundel, Yvan Vander Heyden, Ilse Smolders, Rawi Ramautar, Ann Van Eeckhaut
