The use of medicinal products during pregnancy, lactation, and in young children requires a cautious approach. Due to the unique physiological changes that occur, risk assessments are challenging, necessitating a thorough understanding of the pharmacokinetics and pharmacodynamics of each drug. The group of Eline Tommelein conducts both fundamental and clinical research on the use of medications during these phases of life. The research focuses on ADHD medications, anesthetics, analgesics, and drugs that can affect the hormonal regulation of breastfeeding. In addition, the team performs research on the optimal treatment of conditions that arise during breastfeeding, such as vasospasm, mastitis, and candidiasis of the breast.
Sofie Brouwers' interest in hypertension and how it can be regulated by the brain is long standing. She is interested in how brain mediators interact to control sympathetic tone and blood pressure and may be important in the pathogenesis of many forms of hypertension. She also carries out research into pharmacological and non-pharmacological treatments of high blood pressure to improve the outcome of difficult-to-control hypertensive patients.
